Mannatech Announces Publication of Ambrotose Complex Powder Trial

Robert Sinnott, CEO, MAnnatech


Mannatech announced today the publication of a randomized, double-blind, placebo-controlled human clinical trial showing that intake of a single serving of Ambrotose® complex powder can improve memory.*1

In this study, 73 healthy, mentally fatigued middle-aged adults taking Ambrotose complex experienced statistically significant improvements in their performance on a battery of tests assessing cognitive function, without affecting blood glucose levels.* The study was led by Dr. Talitha Best, a post-doctoral research fellow at the Nutritional Physiology Research Centre, Sansom Institute for Health Research, University of South Australia (UniSA).**

“While the majority of older Americans take dietary supplements to support overall wellness and healthy aging, they are aware of age-related memory problems but haven’t found a supplement that they believe will help,” commented Dr. Robert Sinnott, Mannatech’s CEO and Chief Science Officer. “This study makes it clear that consumers have a product, now backed by three double-blind, placebo-controlled trials, that can provide significant cognitive benefits, both after a single serving1 and long-term intake.” 2, 3

While neuropsychological testing indicates that declines in some aspects of memory function can be detectable as early as one’s 20s and 30s, most people start noticing memory issues about age 50 and thereafter. Given the rapidly-growing number of adults aged 65 and older in the developed world—seniors comprise over 13% of the population in the U.S., Canada and Australia, and 25% of the population in Japan—the need for validated, safe dietary supplements to support healthy cognitive function, a cornerstone of the quality of life, is exploding.

“A healthy lifestyle —one that includes exercise, a healthy diet, no more than moderate alcohol intake, staying mentally active, managing stress, getting adequate sleep, not smoking and staying socially active—can help optimize cognitive function throughout life,” continued Dr. Sinnott. “Our patented, clinically validated Ambrotose products, which have been safely consumed for almost 20 years, are a great choice for people who want to get the most out of their golden years.”

1. Best T, Howe P, Bryan J, Buckley J, Scholey A. Acute effects of a dietary non-starch polysaccharide supplement on cognitive performance in healthy middle-aged adults. Nutr Neurosci 2014;1-11.

2. Best T, Kemps E, Bryan J. Saccharide effects on cognition and well-being in middle-aged adults: A randomized controlled trial. Dev Neuropsych 2010;35:66-80.

3. Best T. An investigation of saccharide effects on memory performance. Abstracts of the 12th Annual Australian Psch Conf 2005;57.

* This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

**Mannatech provided partial funding, and the Ambrotose supplement and placebo, used in this study.

About Mannatech

Mannatech, Incorporated, develops high-quality health, weight and fitness, and skin care products that are based on the solid foundation of nutritional science and development standards. Mannatech is dedicated to its platform of Social Entrepreneurship based on the foundation of promoting, aiding and optimizing nutrition where it is needed most around the world. Mannatech’s proprietary products are available through independent sales Associates around the globe including the United States, Canada, South Africa, Australia, New Zealand, Austria, Denmark, Germany, Norway, Sweden, the Netherlands, the United Kingdom, Japan, Taiwan, Singapore, Estonia, Finland, the Republic of Ireland, Czech Republic, the Republic of Korea, Mexico, Namibia, Hong Kong and Ukraine. 

Please note: This release contains “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933, as amended, Section 21E of the Securities Exchange Act of 1934, as amended, and the Private Securities Litigation Reform Act of 1995. These forward-looking statements generally can be identified by use of phrases or terminology such as “intend” or other similar words or the negative of such terminology. Similarly, descriptions of Mannatech’s objectives, strategies, plans, goals or targets contained herein are also considered forward-looking statements. Mannatech believes this release should be read in conjunction with all of its filings with the United States Securities and Exchange Commission and cautions its readers that these forward-looking statements are subject to certain events, risks, uncertainties and other factors. Some of these factors include, among others, Mannatech’s inability to attract and retain Associates and Members, increases in competition, litigation, regulatory changes and its planned growth into new international markets. Although Mannatech believes that the expectations, statements and assumptions reflected in these forward-looking statements are reasonable, it cautions readers to always consider all of the risk factors and any other cautionary statements carefully in evaluating each forward-looking statement in this release, as well as those set forth in its latest Annual Report on Form 10-K and Quarterly Report on Form 10-Q, and other filings filed with the United States Securities and Exchange Commission, including its current reports on Form 8-K. All of the forward-looking statements contained herein speak only as of the date of this release.

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